This is a practical guide on responding to the challenges of climate change adaptation in cities. The principal intended audience being city officials and practitioners in developing countries, who are beginning to consider the issues and who would find this guide useful to provide an introduction and comprehensive overview of this evolving topic. This guide offers examples of good practices and successful experiences, and describes other available resource materials and tools. In so doing, it can contribute to the development and implementation of adaptation plans in cities, strengthening capacities and helping to catalyze dialogue on adaptation among city managers and other stakeholders.