The sixth annual report on Monitoring progress towards UHC and the health-related SDGs in the South-East Asia Region provides a comprehensive overview on where we are and what is needed to achieve the UHC and health-related SDGs. The report highlights progress in the areas of reproductive, maternal, neonatal and child health, communicable diseases, non-communicable diseases and health systems. This year’s report includes forecasts for progress likely to be achieved towards those health-related SDG indicators where we can model projections to 2030. A section of this report examines health equity and who is being left behind in the Region. The final part of the report provides Member States’ SDG profile, reporting on health and health-related SDGs. The information and analysis in the report can be utilized to sustain and accelerate progress towards Regional Flagship Priorities and the SDG targets.