This document is the second in a series of global reports describing progress towards the 2030 targets set in Ending the neglect to attain the Sustainable Development Goals: a road map for neglected tropical diseases 2021–2030.

This document provides an updated list of “best buys” and other recommended interventions to address noncommunicable diseases (NCDs). It is based on Appendix 3 of the Global action plan for the prevention and control of noncommunicable diseases 2013–2020, which was first approved in 2013 and last updated in 2017.

The number of lives lost due to viral hepatitis infections is increasing and already accounts for 3,500 deaths daily, according to this report by the World Health Organization (WHO).

This document presents the findings of a modelling study that examined in detail the costs and benefits of tuberculosis (TB) screening plus TB preventive treatment (TPT) in four countries – Brazil, Georgia, Kenya and South Africa – which may serve as examples for other settings with a similar epidemiological context.

This brief report summarizes recent information on HIV drug resistance (HIVDR) in the era of integrase-strand transfer inhibitors (INSTI) for HIV prevention and treatment. In this report, WHO documents high levels of HIV viral load suppression (>90%) in populations receiving dolutegravir (DTG)-containing antiretroviral therapy (ART).

Small drinking-water supplies commonly experience operational, managerial, technical and resourcing challenges that impact their ability to deliver safe and reliable services. The needs and opportunities associated with these supplies therefore warrant explicit consideration in policies and regulations.

Neglected tropical diseases (NTDs) are a category of chronic, disabling, and at times disfiguring diseases and conditions that occur most commonly in the setting of extreme poverty. Historically, NTDs have received less attention and funding when compared to other diseases occurring in the same regions of the world.

Health financing is a core pillar of health systems and encompasses the three functions of how revenues for health are collected, pooled and paid out to providers of health care services.

Progress in reducing tobacco use is a key indicator for measuring countries’ efforts to implement the WHO Framework Convention on Tobacco Control – target 3.a under the Sustainable Development Goals agenda.

Primary health care is the best approach to ensure access to equitable health care at a much lower cost. It contributes to substantial reduction in the need for secondary and tertiary care. More importantly, primary health care prepares the health system and health workers as firstline responders for future emergencies.