The fourth edition of the IGAD Regional Focus of the Global Report on Food Crises highlights the alarming high level of acute food insecurity in 2021 in the region, where about 42 million people were estimated to be in Crisis or worse (IPC Phase 3 or above), exceeding the previous three-year high in 2020 by nearly 33 percent. Ethiopia, Kenya, Somalia, South Sudan, and Sudan are facing the largest food crises in the region. About 300,000 people are projected to face Catastrophe (IPC Phase 5) in Somalia and South Sudan in 2022, with a Risk of Famine occurring in eight areas of Somalia through September in the event of widespread crop and livestock production failures, spiralling food costs, and in the absence of scaled-up humanitarian assistance.