Wearable sensor technologies are essential to the realization of personalized medicine through continuously monitoring an individual’s state of health. Sampling human sweat, which is rich in physiological information, could enable non-invasive monitoring. Previously reported sweat-based and other non-invasive biosensors either can only monitor a single analyte at a time or lack on-site signal processing circuitry and sensor calibration mechanisms for accurate analysis of the physiological state.

Shanghai is a low-lying city (3–4 m elevation) surrounded on three sides by the East China Sea, the Yangtze River Estuary, and Hangzhou Bay. With a history of rapid changes in sea level and land subsidence, Shanghai is often plagued by extreme typhoon storm surges. The interaction of sea level rise, land subsidence, and storm surges may lead to more complex, variable, and abrupt disasters. In this paper, we used MIKE 21 models to simulate the combined effect of this disaster chain in Shanghai.