The increasing globalization of food trade has resulted in India being a fast emerging market for probiotic products.

The ICMR guidelines to establish the safety assessment procedures for foods derived from GE plants taking into consideration the international Guideline for the Conduct of Food Safety Assessment of Foods Derived from Recombinant- DNA Plants (CAC 2003b).

The release of revised Ethical guidelines for Biomedical Research on Human subjects by the Council in 2000 was followed by a number of developments in science and technology. These have led to further widening of healthcare between the developed and developing countries. Due to globalization rapid techniques of diagnosis and therapy are now available through R & D.