There is a growing quest for synergy between mitigation and adaptation due to concerns of inefficiency and ineffectiveness of the compartmentalized approaches to climate change. However, little has been done to explore the necessary enabling conditions for synergistic design and implementation. This paper proposes an analytical framework to assess enabling conditions for synergies at the national level and applies it to developing countries to explore the potential move toward synergy. Four enabling conditions for integrating adaptation and mitigation, i.e. policies and strategies, programs and projects, institutional arrangements and financial mechanisms, were used to score developing countries relative to each other. We hypothesized that low income and vulnerable countries might more likely pursue synergy given the urgency for both adaptation and mitigation.