Loss and damage is rapidly gaining prominence in the global climate change arena and is a newly emerging field of research focus. However, the concept behind the idea of residual loss and damage from the impacts of climate change has existed since before the inception of the United Nations Framework Convention on Climate Change (UNFCCC). In 1991, during the drafting of the Convention, the Alliance of Small Island States (AOSIS) proposed the establishment of an international insurance pool to compensate loss and damage from sea level rise (SLR), which was however ultimately not included in the Convention. This paper will provide an overview of loss and damage impacts in South Asia including evidence from the ground, in addition to outlining measures to assess and address loss and damage in the region.