The NATIONAL TUBERCULOSIS INSTITUTE was established in 1959 at Bangalore by the Government of India. The technical assistance in terms of Manpower, Machinery and Equipment from World Health Organization; Vehicle & Equipments from UNICEF were of great asset in the formative years of NTI. This institute is a centre to formulate TB Control Programme best suited to a country like India, where the TB problem is large and the resources are meager. The Institute undertook several Operational Research Studies and evolved a nationally applicable TB Control Programme. Furthermore, the Institute also trains the key personnel to run the programme through District TB Centers. This nationally evolved TB Control Programme has been adopted by several other countries.