The impact of climate change (CC) on water resources is likely to affect agricultural systems and food security. This is especially critical in a least developed country (LDC) like Nepal where a high percentage of the population is dependent on agriculture for its livelihoods. It is, therefore, crucial for Nepal’s leaders and resource managers to draft and begin implementing national adaptation plans. In order for such planning to be effective, it is critical to gain a more comprehensive understanding of the anticipated impacts of CC and the institutions potentially involved in the adaptation process. This working paper aims to create a more comprehensive understanding of how the impacts of CC will be realized at different scales in Nepal, from household livelihoods to national food security, and the many institutions governing the ultimate adaptation process.