Electric buses could pioneer a new age of clean and efficient urban transport and put cities on track towards sustainability. However, electric bus adoption is not accelerating fast enough for the world to meet transport-related global climate objectives and help limit global temperature rise to below 2 degrees Celsius. The aim of this report is to fill in knowledge gaps and provide actionable guidance for transit agencies and bus operating entities to help them overcome the most common and debilitating barriers to electric bus adoption. It provides a step-by-step guidance to establish and achieve electric bus adoption targets using concrete and diverse real-world experiences. Transit agencies and bus operating entities are encouraged to maximize electric bus adoption targets based on local conditions and to develop a responsible strategy for implementation. They should be actively involved in planning and analysis; be serious about piloting and testing projects; and collaborate with city policymakers and other stakeholders to accelerate a responsible adoption of electric buses.