Groundwater is a life-sustaining resource that supplies water to billions of people, plays a central part in irrigated agriculture and influences the health of many ecosystems. Most assessments of global water resources have focused on surface water but unsustainable depletion of groundwater has recently been documented on both regional and global scales. It remains unclear how the rate of global groundwater depletion compares to the rate of natural renewal and the supply needed to support ecosystems.