Recent years have shown increased awareness that the use of the basic resources water, food, and energy are highly interconnected (referred to as a ‘nexus’). Spatial scales are an important but complicating factor in nexus analyses, and should receive more attention – especially in the policy-oriented literature. In this paper, we ‘unpack' the nexus concept, aiming to understand the differences between water, food and energy resources, especially in terms of spatial scales.