The 19 case studies presented in this report showcase good practice in addressing the challenges of climate change. They focus on: expanding and improving activities to prepare for and respond to climate risks; and livelihood strengthening, natural resource management and health related adaptation projects, notably to secure sustainable sources of food and water security and build resilience to climate change. The report intends to be a mechanism for sharing knowledge and experience between agencies and regions, and aims at serving to inform future adaptation action. It is part of a regional and national level consultation process started by the IASC Task Force on Climate Change together with the UNISDR to reflect upon the humanitarian challenges of climate change, and to discuss approaches and good practices for addressing these.