Understanding of the factors driving global antimicrobial resistance is limited. We analysed antimicrobial resistance and antibiotic consumption worldwide versus many potential contributing factors.

Original Source

Until now, polymyxin resistance has involved chromosomal mutations but has never been reported via horizontal gene transfer. During a routine surveillance project on antimicrobial resistance in commensal Escherichia coli from food animals in China, a major increase of colistin resistance was observed. When an E coli strain, SHP45, possessing colistin resistance that could be transferred to another strain, was isolated from a pig, we conducted further analysis of possible plasmid-mediated polymyxin resistance.

Gram-negative Enterobacteriaceae with resistance to carbapenem
conferred by New Delhi metallo-?-lactamase 1 (NDM-1) are potentially a
major global health problem. The researchers investigated the prevalence of NDM-1,
in multidrug-resistant Enterobacteriaceae in India, Pakistan, and the