This study focuses on the binding affinity of chemicals that are the components of widely used cosmetics, with human DNA and CYP1A2 protein, which is involved in there deactivation and excretion. Study was carried on the 21 selected possibly toxic chemicals which may be involved in DNA adduct formation and show possible proteins binding affinity, then a docking analysis has been performed by an automated docking server known as Patchdock. The five chemicals with highest Patch Dock scores with both DNA and CYP1A2 were mostly found to be important ingredient of many cosmetic products.

The researchers measured lead and eight other metals in a convenience sample of 32 lip products used by young Asian women in Oakland, California, USA, and assessed potential health risks related to estimated intakes of these metals.

Original Source

Rabbit skin model was used to test skin irritation of the most commonly used cosmetic products in Jimma town, southwestern Ethiopia. The most commonly used cosmetics were Dove, Glysolid, College, Top Society, Fair and Lovely, Nivea, Lux, Magic fruit world, Solea, Body talk, Kris, Holly, Victoria, and Sweet Heart. Methods. Intact and abraded rabbit skins were tested for erythema and edema under shade and under sun exposure. Draize Primary Irritation Index (PII) was used to calculate skin irritation of each cosmetic. Cosmetic ingredients were analyzed from the labels. Results and Discussion.

Data concerning the effects of prenatal exposures to phthalates and phenols on fetal growth are limited in humans. Previous findings suggest possible effects of some phenols on male birth weight. The aim of the study was to assess the relationships between prenatal exposures to phthalates and phenols and fetal growth among male newborns.