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Developed by NewClimate Institute and Germanwatch, the index ties in with the global Climate Change Performance Index by Germanwatch, a rating of the 58 largest emitters of GHG emissions globally that has been published annually since 2006. This special edition now focuses on the 20 largest economies (G20). The methodology was also adjusted.

Four Indian renewable power producers are planning to raise up to $2.5 billion via dollar bonds offshore because of caution among domestic lenders, banking sources said.

Transcription factor AP-1 plays a central role in HPV-mediated cervical carcinogenesis. AP-1 has also been implicated in chemo-radio-resistance but the mechanism(s) remained unexplored. In the present study, cervical cancer stem-like cells (CaCxSLCs) isolated and enriched from cervical cancer cell lines SiHa and C33a demonstrated an elevated AP-1 DNA-binding activity in comparison to non-stem cervical cancer cells.

All UN member states are committed to achieve SDGs Agenda 2030 consisting of 17 goals and 169 targets, spanning the three dimensions of economic, social and environmental development.

ideR, an essential gene of Mycobacterium tuberculosis, is an attractive drug target as its conditional knockout displayed attenuated growth phenotype in vitro and in vivo. To the best of our knowledge, no inhibitors of IdeR are identified. We carried out virtual screening of NCI database against the IdeR DNA binding domain followed by inhibition studies using EMSA. Nine compounds exhibited potent inhibition with NSC 281033 (I-20) and NSC 12453 (I-42) exhibiting IC50 values of 2 µg/ml and 1 µg/ml, respectively.

The best available science shows an urgent need to keep global temperature increases below 1.5°C to avoid severe disruptions to people and ecosystems. Recent analysis shows that burning the reserves in already operating oil and gas fields alone, even if coal mining is completely phased out, would take the world beyond 1.5°C of warming.

The global use of untreated waste water from cities to irrigate crops is much more widespread than previously estimated, says a new report.

A new report examines how to support the successful integration of Nationally Determined Contributions (NDCs) into national development planning. The adoption of the Paris Agreement in 2015 signalled a major transition in the international climate change governance regime.

Seven of the nine 'high-focus' states report underspending on healthcare

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