Despite dramatic progress against it, malaria still kills nearly half a million people a year, over 90 percent of them children in sub Saharan Africa. Almost all those deaths are preventable.

Mathabire, who works with Doctors Without Borders (MSF), won the HIV/TB research prize for her groundbreaking HIV/TB research on the use of a portable test for TB among severely ill HIV patients in

Doctors report unusual symptomatic manifestations

Coimbatore: The National Institute of Malaria Research (Nimr), a research institution of the Indian Council of Medical Research (Icmr), is planning to set up a malaria research centre on the Coimba

Scientists in The Gambia have come up with new innovative solutions to help stop the spread of malaria.

Dr Rakesh K Mishra CCMB director said the finding will help in accelerating efforts for predictive and personalised genomic medicines.

Basic ingredient of turmeric, in the form studied, is understood to be five times more ‘bioavailable’ in mice than in the regular one

Transcription factor AP-1 plays a central role in HPV-mediated cervical carcinogenesis. AP-1 has also been implicated in chemo-radio-resistance but the mechanism(s) remained unexplored. In the present study, cervical cancer stem-like cells (CaCxSLCs) isolated and enriched from cervical cancer cell lines SiHa and C33a demonstrated an elevated AP-1 DNA-binding activity in comparison to non-stem cervical cancer cells.

ideR, an essential gene of Mycobacterium tuberculosis, is an attractive drug target as its conditional knockout displayed attenuated growth phenotype in vitro and in vivo. To the best of our knowledge, no inhibitors of IdeR are identified. We carried out virtual screening of NCI database against the IdeR DNA binding domain followed by inhibition studies using EMSA. Nine compounds exhibited potent inhibition with NSC 281033 (I-20) and NSC 12453 (I-42) exhibiting IC50 values of 2 µg/ml and 1 µg/ml, respectively.

Diagnosis is complicated due to challenges associated with sample collection

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