Previous efforts to report estimates of cancer incidence and mortality in India and its different parts include the National Cancer Registry Programme Reports, Sample Registration System cause of death findings, Cancer Incidence in Five Continents Series, and GLOBOCAN. We present a comprehensive picture of the patterns and time trends of the burden of total cancer and specific cancer types in each state of India estimated as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 because such a systematic compilation is not readily available.

The relatively high incidence of cervical cancer in women at older ages is a continuing concern in countries with long-established cervical screening. Controversy remains on when and how to cease screening. Existing population-based studies on the effectiveness of cervical screening at older ages have not considered women’s screening history. We performed a nationwide cohort study to investigate the incidence of cervical cancer after age 60 years and its association with cervical screening at age 61–65, stratified by screening history at age 51–60.

Transcription factor AP-1 plays a central role in HPV-mediated cervical carcinogenesis. AP-1 has also been implicated in chemo-radio-resistance but the mechanism(s) remained unexplored. In the present study, cervical cancer stem-like cells (CaCxSLCs) isolated and enriched from cervical cancer cell lines SiHa and C33a demonstrated an elevated AP-1 DNA-binding activity in comparison to non-stem cervical cancer cells.

Judgement of the Supreme Court of India in the matter of Kalpana Mehta & Others Vs Union of India & Others dated 05/04/2017 regarding approval of Human Papilloma Virus (HPV) vaccine manufactured by M/s. GlaxoSmithKline Asia Pvt. Ltd. and MSD Pharmaceuticals Private Limited for preventing cervical cancer in women and the experimentation of the vaccine by the Governments of Gujarat and Andhra Pradesh. The case also deals with the untimely death of certain persons and grant of compensation. 


Over the last two decades, ovarian cancer mortality rates have levelled or declined. There are, however, persisting and substantial differences in ovarian cancer patterns and trends. Researchers updated global trends in ovarian cancer mortality to 2012, and predicted trends in rates to 2020 using data from the World Health Organization database.

Original Source

European guidelines recommend the routine offer of an HIV test in patients with a number of AIDS-defining and non-AIDS conditions believed to share an association with HIV; so called indicator conditions (IC). Adherence with this guidance across Europe is not known. We audited HIV testing behaviour in patients accessing care for a number of ICs.

Original Source

Worldwide data for cancer survival are scarce. The researchers aimed to initiate worldwide surveillance of cancer survival by central analysis of population-based registry data, as a metric of the effectiveness of health systems, and to inform global policy on cancer control.

Question raised in Rajya Sabha on high rate of cervical cancer in India, 12/08/2014.

Petition filed in the Circuit Court of the City of St. Louis State of Missouri in the matter of Angie Wait & Others Vs Johnson & Johnson dated 23/06/2014 regarding linkage between talcum powder and ovarian cancer. All Plaintiffs in this action are seeking "recovery for damages as a result of developing ovarian cancer, which was directly and proximately caused by such wrongful conduct by Johnson & Johnson, the unreasonably dangerous and defective nature of talcum powder, and the attendant effects of developing ovarian cancer".

Epidemic of cancer has transited beyond the geographical boundaries of countries. The globe is under the clutch of this dreadful disease which is spreading rapidly. Nevertheless it is a challenge for any health care system. Every year nearly 10 million people are being diagnosed with cancer out of which about 6 million die per year (Khanna, 2005). Though cancer prevalence in India is less compared to developed countries, it has increased grossly during past few decades.