Even a cure is not preventing deaths from malaria in Uganda. Poor education and limited access to healthcare are among the reasons why.

Nature Outlook maps the challenges in tackling the malaria epidemic.

Data on insecticide use for vector control are essential for guiding pesticide management systems on judicious and appropriate use, resistance management, and reduction of risks to human health and the environment. The researchers studied the global use and trends of insecticide use for control of vector-borne diseases for the period 2000 through 2009.

Aedes aegypti dispersion is the major reason for the increase in dengue transmission in South America. In Brazil, control of this mosquito strongly relies on the use of pyrethroids and organophosphates against adults and larvae, respectively. In consequence, many Ae. aegypti field populations are resistant to these compounds. Resistance has a significant adaptive value in the presence of insecticide treatment.

Malaria is an ancient disease in India. Known as the ‘king of diseases’, malaria was estimated to cause 75 million cases and 0.8 million deaths annually. In epidemic years, morbidity and mortality used to increase 2–3 times. Ravages of malaria were so rampant and devastating, that the economic growth of the country remained paralysed.

The prevalence of malaria among the residents of the Lake Victoria basin remains high. The environment associated with the lake may maintain a high number of malaria vectors. Lake habitats including water hyacinths have been suspected to be the source of vectors. This study investigated whether malaria vectors breed in the lake habitats and adjacent backwater pools. Anopheline larvae were collected within the littoral zone of the lake and adjacent pools located along approximately 24.3 km of the lakeshore in western Kenya, and their breeding sites characterized.

Differences between individual human houses can confound results of studies aimed at evaluating indoor vector control interventions such as insecticide treated nets (ITNs) and indoor residual insecticide spraying (IRS). Specially designed and standardised experimental huts have historically provided a solution to this challenge, with an added advantage that they can be fitted with special interception traps to sample entering or exiting mosquitoes.