Diet is a key modifiable risk factor for multiple chronic conditions, including type 2 diabetes (T2D). Consuming a range of foods from the five major food groups is advocated as critical to healthy eating, but the association of diversity across major food groups with T2D is not clear and the relationship of within-food-group diversity is unknown. In addition, there is a growing price gap between more and less healthy foods, which may limit the uptake of varied diets.

In our first study on possible flood damages under climate change in Germany, we reported that a considerable increase in flood-related losses can be expected in a future warmer climate. However, the general significance of the study was limited by the fact that outcome of only one global climate model (GCM) was used as a large-scale climate driver, while many studies report that GCMs are often the largest source of uncertainty in impact modelling.

The recent explosive outbreak of Zika virus (ZIKV) infection has been reported in South and Central America and the Caribbean. Neonatal microcephaly associated with ZIKV infection has already caused a public health emergency of international concern. No specific vaccines or drugs are currently available to treat ZIKV infection. The ZIKV helicase, which plays a pivotal role in viral RNA replication, is an attractive target for therapy.

Original Source

A novel nested flood model (MSN_Flood) is applied to simulate complex coastal-fluvial urban flooding in order to critically examine the model's capability to forecast evolution of urban inundation. The model demonstrates high accuracy of outputs without incurring the computational expense of high spatial resolution over the entire model domain. MSN_Flood provides full characteristics of water levels and flow regimes necessary for flood hazard identification and flood risk assessment.

The objective of the study was to extend a nation-wide rotavirus surveillance network in India, and to generate geographically representative data on rotaviral disease burden and prevalent strains.

Original Source

Tropical cyclones play an important role in modifying the tropopause structure and dynamics as well as stratosphere–troposphere exchange (STE) processes in the upper troposphere and lower stratosphere (UTLS) region. In the present study, the impact of cyclones that occurred over the north Indian Ocean during 2007–2013 on the STE processes is quantified using satellite observations.

Animal populations occurring at high elevations are often assumed to be in peril of extinctions or local extirpations due to elevational-dispersal limitations and thermoregulatory constraints as habitats change and warm. However, long-term monitoring of high-elevation populations is uncommon relative to those occurring at lower elevations, and evidence supporting this assumption is limited. We analyzed 45 years of reproductive data for two Colorado populations of white-tailed ptarmigan (Lagopus leucura), an alpine-endemic species with restricted distribution in western North America.

WHO recommends combinations of an artemisinin derivative plus an antimalarial drug of longer half-life as treatment options for uncomplicated Plasmodium falciparum infection. In Africa, artemether–lumefantrine is the most widely used artemisinin-based combination therapy, whereas artesunate–mefl oquine is used infrequently because of a perceived poor tolerance to mefl oquine. WHO recommends reconsideration of the use of artesunate– mefl oquine in Africa.

The present study has generated and analyzed Climate Change projections in Nicaragua for the period 2010-2040. The obtained results are to be used for evaluating and planning more resilient transport infrastructures in the next decades. This study has focused its efforts to pay attention into the effect of Climate Change on precipitation and temperature from a mean and extreme event perspective.

The mass extinction of life 66 million years ago at the Cretaceous/Paleogene boundary, marked by the extinctions of dinosaurs and shallow marine organisms, is important because it led to the macroevolution of mammals and appearance of humans. The current hypothesis for the extinction is that an asteroid impact in present-day Mexico formed condensed aerosols in the stratosphere, which caused the cessation of photosynthesis and global near-freezing conditions. Here, we show that the stratospheric aerosols did not induce darkness that resulted in milder cooling than previously thought.