Air pollution is hypothesized to be a risk factor for diabetes. Epidemiological evidence is inconsistent and has not been systematically evaluated.

An urgent need exists to identify modifiable dietary risk factors for obesity in African-Americans. Human observations since the 1980’s of lower levels of 25-hydroxyvitamin D25(OH)D in obese than in nonobese individuals highlight a possible inverse relation between vitamin D and obesity.

The search for effective treatments for obesity and its comorbidities is of prime importance. We previously identified ​IKK-ε and ​TBK1 as promising therapeutic targets for the treatment of obesity and associated insulin resistance. Here we show that acute inhibition of ​IKK-ε and ​TBK1 with ​amlexanox treatment increases ​cAMP levels in subcutaneous adipose depots of obese mice, promoting the synthesis and secretion of the cytokine ​IL-6 from adipocytes and preadipocytes, but not from macrophages.

Diabetes and hypertension is affecting at an alarming rate in both rural and urban populations in India and very few studies had been carried out among the tribal population. The objective of the study was to determine the prevalence rate of type 2 diabetes mellitus and hypertension and its associated risk factors among the tribal population in Salem District in Tamil Nadu.