Plastic waste can promote microbial colonization by pathogens implicated in outbreaks of disease in the ocean. We assessed the influence of plastic waste on disease risk in 124,000 reef-building corals from 159 reefs in the Asia-Pacific region. The likelihood of disease increases from 4% to 89% when corals are in contact with plastic. Structurally complex corals are eight times more likely to be affected by plastic, suggesting that microhabitats for reef-associated organisms and valuable fisheries will be disproportionately affected.

Healthy marine ecosystems are crucial for people’s livelihoods and food production. Global climate stressors, such as warming and ocean acidification, can drastically impact the structure and function of marine food webs, diminishing the production of goods and services. Our ability to predict how future food webs will respond to a changing environment is limited by our understanding of species responses to climate change, which are often tested in isolation or in simplified experimental designs.