Venomous snakebite is a global serious health issue and in India high rate of mortality is caused by Naja naja (Indian cobra). To evaluate anti-cobra venom activity and identify lead molecules in Aegle marmelos, in vitro and in silico screening was carried out. Leaves, stem and root bark of A. marmelos were extracted in ethanol, methanol and hexane and maximum yield was obtained in methanol.

Original Source

The Global Burden of Disease Study (GBD) is generating important and often nonintuitive information about the prevalence, incidence, morbidity, and mortality of the world’s major communicable and noncommunicable diseases (NCDs). An emerging narrative from the GBD is the gradual ascendency of the NCDs, especially among the world’s large low- and middle-income countries (LMICs). But with regards to the neglected tropical diseases (NTDs), we have also seen how these chronic and debilitating infections of poverty might also account for a high percentage of the global disease burden.

Progress towards the elimination of a neglected tropical disease from a country can sometimes be a curse, especially when policymakers are confronted with competing needs and priorities. This could mistakenly be interpreted as though the disease has been eradicated, resulting in the limited resources becoming redirected to the next priority, sometimes leaving unfinished agendas. Much depends on whether the long term is considered in the elimination agenda and whether contingency plans are in place should the disease re-emerge as a public health problem.