The end-Permian mass extinction not only decimated taxonomic diversity but also disrupted the functioning of global ecosystems and the stability of biogeochemical cycles. Explaining the 5-million-year delay between the mass extinction and Earth system recovery remains a fundamental challenge in both the Earth and biological sciences. We use coupled records of uranium concentrations and isotopic compositions to constrain global marine redox conditions across the end-Permian extinction horizon and through the subsequent 17 million years of Earth system recovery.

The genetic underpinnings associated with the earliest stages of plant and animal domestication have remained elusive. Because a genome-wide response to selection can take many generations, the earliest detectable changes associated with domestication may first manifest as heritable changes to global patterns of gene expression. Here, to test this hypothesis, we measured differential gene expression in the offspring of wild and first-generation hatchery steelhead trout (Oncorhynchus mykiss) reared in a common environment.

Reservoirs of infectious HIV-1 persist despite years of combination antiretroviral therapy and make curing HIV-1 infections a major challenge. Most of the proviral DNA resides in CD4+T cells. Some of these CD4+T cells are clonally expanded; most of the proviruses are defective. It is not known if any of the clonally expanded cells carry replication-competent proviruses. We report that a highly expanded CD4+ T-cell clone contains an intact provirus.

As planetary boundaries are rapidly being approached, humanity has little room for additional expansion and conventional intensification of agriculture, while a growing world population further spreads the food gap. Ample evidence exists that improved on-farm water management can close water-related yield gaps to a considerable degree, but its global significance remains unclear.

With the formation of the World Trade Organization in 1995, the United States farm subsidies had moved towards income support, reducing spending on price support measures. The explicit reason was that the WTO had held that the latter forms were more market distorting and had thus put limits on their spending. The new Farm Act 2014 has changed the orientation of farm spending in the opposite direction. Pricebased measures are back in focus, and the US seems less concerned about breaching its WTO limits.

This article investigates the impact of court verdicts on Chennai’s canals, tanks and related wetlands. It discusses three interlinked cases surrounding Buckingham Canal area and argues that the verdicts in these cases allowed the administration to destroy sophisticated water systems. It also argues that these waterbodies could have mitigated, if not prevented, the November–December 2015 fl oods in Chennai.

The pattern of epidemic meningococcal disease in the African meningitis belt may be influenced by the background level of population immunity but this has been measured infrequently. A standardised enzyme-linked immunosorbent assay (ELISA) for measuring meningococcal serogroup A IgG antibodies was established at five centres within the meningitis belt. Antibody concentrations were then measured in 3930 individuals stratified by age and residence from six countries. Seroprevalence by age was used in a catalytic model to determine the force of infection.

On September 14, 2015 at 09:50:45 UTC the two detectors of the Laser Interferometer Gravitational-Wave Observatory simultaneously observed a transient gravitational-wave signal. The signal sweeps upwards in frequency from 35 to 250 Hz with a peak gravitational-wave strain of 1.0 × 10−21. It matches the waveform predicted by general relativity for the inspiral and merger of a pair of black holes and the ringdown of the resulting single black hole.

Myopia is a common cause of vision loss, with uncorrected myopia the leading cause of distance vision impairment globally. Individual studies show variations in the prevalence of myopia and high myopia between regions and ethnic groups, and there continues to be uncertainty regarding increasing prevalence of myopia.

Original Source

Large magnitude earthquakes in urban environments continue to kill and injure tens to hundreds of thousands of people, inflicting lasting societal and economic disasters. Earthquake early warning (EEW) provides seconds to minutes of warning, allowing people to move to safe zones and automated slowdown and shutdown of transit and other machinery. The handful of EEW systems operating around the world use traditional seismic and geodetic networks that exist only in a few nations.