Exposure to high concentrations of persistent organochlorines may cause fetal toxicity, but the evidence at low exposure levels is limited. Large studies with substantial exposure contrasts and appropriate exposure assessment are warranted.

Obesity has risen steadily in the United States over the past 150 years, with a marked uptick in recent decades. In the United States today more than 35% of adults and nearly 17% of children aged 2–19 years are obese. Obesity plagues people not just in the United States but worldwide, including, increasingly, developing countries. Even animals—pets, laboratory animals, and urban rats—have experienced increases in average body weight over the past several decades, trends not necessarily explained by diet and exercise. In the words of Robert H.

When it comes to health, which is more important, nature or nurture? You may well think your genes are a more important predictor of health and ill health. Not so fast. In fact, it transpires that our everyday environment outweighs our genetics, big time, when it comes to measuring our risk of disease. The genome is out - welcome the exposome.