North America is in the midst of its most serious drug-overdose crisis in history. From 1999 through 2015, drug-overdose deaths approximately tripled in the United States, and the majority of such deaths now involve an opioid. In 2016 alone, there were 64,000 drug-overdose deaths in the United States — more than the total number of U.S. military deaths during the Vietnam War. As a result, and despite gains in other areas of medicine and public health, the United States recently experienced its first major decline in life expectancy since 1993.

To many, cannabis is a recreational drug; to some, it is a medicine. Now, it is increasingly seen as a crop, to be grown in quantity and engineered for better traits—not just pharmacological effects, but also fiber content and the rapid, efficient growth that makes a plant useful for biofuels. This month, in a special issue of Critical Reviews in Plant Sciences, researchers delve into all aspects of cannabis biology and ecology. The work sheds light on how the plant has diversified since it was first grown 8500 years ago in Eurasia.

Judgement of the Supreme Court of India in the matter of Bachpan Bachao Andolan Vs Union of India & Others dated 14/12/2016 regarding alarming increase in the use of drugs and alcohol among children in India. The Union Government has stated before the Supreme Court that a national policy on drug demand reduction is being finalized. The priority areas of intervention would include capacity building and training of service providers with a view to build up skilled manpower, education and awareness building at all levels and inter-sectoral collaboration.

Order of the High Court of Uttarakhand at Nainital dated 25/10/2016 regarding availability of Iodex, Fevi-Quick and any other adhesive solutions to children below the age of 18 years.

Chief Secretary, State of Uttarakhand is directed by the Court to ensure that the Iodex, Fevi-Quick and any other adhesive solutions are not sold to the boys and girls below the age of 18 years. Since, the use of whitener has become obsolete, the sale of the same is banned throughout the State of Uttarakhand.

Cannabis agriculture is a multi-billion dollar industry in the United States that is changing rapidly with policy liberalization. Anecdotal observations fuel speculation about associated environmental impacts, and there is an urgent need for systematic empirical research. An example from Humboldt County California, a principal cannabis-producing region, involved digitizing 4428 grow sites in 60 watersheds with Google Earth imagery. Grows were clustered, suggesting disproportionate impacts in ecologically important locales.

Despite evidence of substantial comorbidity between psychiatric disorders and substance involvement, the extent to which common genetic factors contribute to their co-occurrence remains understudied. In the current study, we tested for associations between polygenic risk for psychiatric disorders and substance involvement (i.e., ranging from ever-use to severe dependence) among 2573 non-Hispanic European–American participants from the Study of Addiction: Genetics and Environment.

Mental, neurological, and substance use (MNS) disorders are highly prevalent and are responsible for 14% of the global burden of disease expressed in disability-adjusted life years (DALYs). The resources that have been provided in countries to tackle the huge burden are insufficient, inequitably distributed, and inefficiently used, which results in a large majority of people with these disorders receiving no care at all. Even when available, treatment and care often is neither evidence-based nor of high quality.

patent Human genes create stir in US About 100,000 cancer patients, doctors, researchers and lawyers sued the US government for granting patents for two human genes. They said the patents deny women with breast and ovarian cancer the benefit of new tests and possible treatment. A company or an institution that owns patents for genes has specific rights to their use, which may

Hub of illicit drug trade: Criminal networks in Africa are setting up fake pharmaceutical companies as a front to trade in substances used to make street methamphetamines, a psychostimulant, the International Narcotics Control Board

Marijuana to cancer: Scientists in Seattle have found that young men smoking marijuana were at a higher risk of developing an aggressive form of testicular cancer called nonseminoma than those who had never tried the drug. The disease is known to strike men in there 20s and 30s and is the most common type of cancer among men in the UK, the researchers said. The study, published in the journal

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