Efforts to make heritable changes to the human genome are fraught with uncertainty. Here’s what it would take to make the technique safe and acceptable.

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An Aerodyne high-resolution time-of-flight aerosol mass spectrometer (HR-ToF-AMS) was deployed along with other online instruments to study the highly time resolved chemistry and sources of submicron aerosols (PM1) at Waliguan (WLG) Baseline Observatory, a high-altitude (3816 m a.s.l.) background station located at the northeast edge of the Qinghai–Tibet Plateau (QTP), during 1–31 July 2017.

This paper assessed the variability and projected trends of solar irradiance and temperature in the East of Burundi. Observed temperature from meteorological stations and the MERRA-2 data set provided by NASA/Goddard Space Flight Center are used over the historical period 1976–2005.

We use 2010–2015 observations of atmospheric methane columns from the GOSAT satellite instrument in a global inverse analysis to improve estimates of methane emissions and their trends over the period, as well as the global concentration of tropospheric OH (the hydroxyl radical, methane's main sink) and its trend. Our inversion s

An atmospheric inversion was performed for the city of Cape Town for the period of March 2012 to June 2013, making use of in situ measurements of CO2 concentrations at temporary measurement sites located to the north-east and south-west of Cape Town. This paper presents results of sensitivity analyses that tested assumptions

Unconventional shale gas development is a rapidly expanding driver of forest loss and fragmentation in the central Appalachian region. The researchers evaluated the relationship between breeding passerine abundances and distance from shale gas development at a long-term (2008–2017) study site in northern West Virginia, USA.

The number of cancer survivors continues to increase in the United States because of the growth and aging of the population as well as advances in early detection and treatment. To assist the public health community in better serving these individuals, the American Cancer Society and the National Cancer Institute collaborate every 3 y

Vaccines have revolutionized public health, preventing millions of deaths each year, particularly in childhood. Yet, there is considerable variability in the magnitude and persistence of vaccine-induced immunity. Maintenance of specific antibody is essential for continuity of vaccine-induced serological protection.

Rhino- and enteroviruses are important human pathogens, against which no antivirals are available. The best-studied inhibitors are “capsid binders” that fit in a hydrophobic pocket of the viral capsid.

Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse.