Data from different national and regional surveys show that hypertension is common in developing countries, particularly in urban areas, and that rates of awareness, treatment, and control are low. Several hypertension risk factors seem to be more common in developing countries than in developed regions. Findings from serial surveys show an increasing prevalence of hypertension in developing countries, possibly caused by urbanisation, ageing of population, changes to dietary habits, and social stress.

Obesity is a significant public health issue. Marion Nestle spoke with Ben Jones about calories and why anti-obesity measures must prevail.

Physical inactivity accounts for more than 3 million deaths per year, most from non-communicable diseases in low-income and middle-income countries. We used reviews of physical activity interventions and a simulation model to examine how megatrends in information and communication technology and transportation directly and indirectly affect levels of physical activity across countries of low, middle, and high income.

Humans evolved to run. This helps to explain our athletic capacity and our susceptibility to modern diseases, argue Timothy Noakes and Michael Spedding.

In an article that forms part of the PLoS Medicine series on Big Food, Corinna Hawkes and colleagues provide a perspective from South Africa on the rise of multinational and domestic food companies, and argue that government should act urgently through education about the health risks of unhealthy diets, regulation of Big Food, and support for healthy foods.

In an article that forms part of the PLoS Medicine series on Big Food, Kelly Brownell offers a perspective on engaging with the food industry, and argues that governments and the public health community should be working for regulation, not collaboration.